Plasminogen (medication)
| Plasminogen (medication) | |
|---|---|
| [[File:|frameless|220px|alt=|]] | |
| INN | |
| Drug class | |
| Routes of administration | |
| Pregnancy category | |
| Bioavailability | |
| Metabolism | |
| Elimination half-life | |
| Excretion | |
| Legal status | |
| CAS Number | |
| PubChem | |
| DrugBank | |
| ChemSpider | |
| KEGG | |
Plasminogen is a medication used in the treatment of certain medical conditions related to fibrinolysis. It is a precursor to plasmin, an important enzyme that breaks down fibrin clots. This medication is primarily used in the management of hypoplasminogenemia, a rare condition characterized by low levels of plasminogen in the blood.
Mechanism of Action
Plasminogen is converted into its active form, plasmin, by tissue plasminogen activator (tPA) or urokinase. Plasmin then degrades fibrin, a key component of blood clots, into soluble fragments. This process is crucial for the maintenance of normal blood flow and prevention of thrombosis.
Indications
Plasminogen is indicated for use in patients with congenital plasminogen deficiency, which can lead to the development of ligneous conjunctivitis, a condition characterized by the formation of wood-like pseudomembranes on the conjunctiva.
Administration
Plasminogen is administered via intravenous infusion. The dosage and frequency depend on the severity of the deficiency and the clinical response of the patient.
Side Effects
Common side effects of plasminogen therapy may include allergic reactions, fever, and headache. Serious side effects are rare but can include anaphylaxis and thrombosis.
Contraindications
Plasminogen should not be used in patients with known hypersensitivity to the drug or any of its components. It is also contraindicated in patients with active bleeding disorders.
See Also
References
External Links
Transform your life with W8MD's budget GLP-1 injections from $125.
W8MD offers a medical weight loss program to lose weight in Philadelphia. Our physician-supervised medical weight loss provides:
- Most insurances accepted or discounted self-pay rates. We will obtain insurance prior authorizations if needed.
- Generic GLP1 weight loss injections from $125 for the starting dose.
- Also offer prescription weight loss medications including Phentermine, Qsymia, Diethylpropion, Contrave etc.
NYC weight loss doctor appointments
Start your NYC weight loss journey today at our NYC medical weight loss and Philadelphia medical weight loss clinics.
- Call 718-946-5500 to lose weight in NYC or for medical weight loss in Philadelphia 215-676-2334.
- Tags:NYC medical weight loss, Philadelphia lose weight Zepbound NYC, Budget GLP1 weight loss injections, Wegovy Philadelphia, Wegovy NYC, Philadelphia medical weight loss, Brookly weight loss and Wegovy NYC
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
