Piloleiomyoma
Piloleiomyoma
Piloleiomyoma (pronounced: pi-lo-lei-o-my-o-ma) is a type of cutaneous leiomyoma, a benign tumor that originates from the arrector pili muscle in the hair follicle.
Etymology
The term "Piloleiomyoma" is derived from the Latin words 'pilo', meaning hair, 'leiomyo', referring to smooth muscle, and 'oma', indicating a tumor. Thus, the term literally translates to a hair smooth muscle tumor.
Description
Piloleiomyomas are typically small, firm, skin-colored or brownish nodules or papules. They are often multiple and can be found anywhere on the body, but are most commonly located on the extremities. The lesions may be painful, particularly in response to cold or tactile stimuli.
Diagnosis
Diagnosis of piloleiomyoma is typically made based on clinical examination and confirmed by histopathology. The histopathological examination reveals interlacing bundles of smooth muscle fibers, which are positive for desmin and smooth muscle actin on immunohistochemical staining.
Treatment
Treatment options for piloleiomyoma include surgical excision, laser therapy, and pharmacological management with medications such as calcium channel blockers and alpha-adrenergic blockers.
Related Terms
- Cutaneous leiomyoma
- Arrector pili muscle
- Hair follicle
- Tumor
- Histopathology
- Desmin
- Smooth muscle actin
- Calcium channel blockers
- Alpha-adrenergic blockers
External links
- Medical encyclopedia article on Piloleiomyoma
- Wikipedia's article - Piloleiomyoma
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