Phorate
Phorate
Phorate is a highly toxic organophosphate insecticide and acaricide used to control a wide range of pests on various crops. It is known for its effectiveness against insects such as aphids, mites, and thrips. Due to its high toxicity, phorate is classified as a restricted use pesticide in many countries.
Chemical Properties
Phorate is an organophosphate compound with the chemical formula C7H17O2PS3. It is a colorless to pale yellow liquid with a strong odor. The compound is soluble in organic solvents but has low solubility in water.
Mechanism of Action
Phorate acts by inhibiting the enzyme acetylcholinesterase, which is essential for the proper functioning of the nervous system in insects. By blocking this enzyme, phorate causes an accumulation of acetylcholine at the synapses, leading to continuous nerve impulse transmission, paralysis, and eventually death of the pest.
Usage and Application
Phorate is primarily used in agriculture to protect crops such as corn, cotton, potatoes, and soybeans from insect damage. It is applied to the soil or as a seed treatment to provide systemic protection to the plants.
Safety and Environmental Impact
Due to its high toxicity, phorate poses significant risks to human health and the environment. It can cause acute poisoning in humans if ingested, inhaled, or absorbed through the skin. Symptoms of phorate poisoning include headache, dizziness, nausea, and in severe cases, respiratory failure.
Phorate is also highly toxic to wildlife, particularly birds and aquatic organisms. Its use is regulated to minimize environmental contamination and protect non-target species.
Regulatory Status
Phorate is subject to strict regulations in many countries due to its potential health and environmental hazards. It is classified as a restricted use pesticide, meaning it can only be applied by certified applicators who have received special training in handling and applying such chemicals safely.
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Contributors: Prab R. Tumpati, MD