Adenovirus infection
(Redirected from Pharyngoconjunctival fever)
| Adenovirus infection | |
|---|---|
| |
| Synonyms | N/A |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Fever, sore throat, conjunctivitis, gastroenteritis, respiratory illness |
| Complications | Pneumonia, bronchiolitis, meningitis |
| Onset | 2-14 days after exposure |
| Duration | 1-2 weeks |
| Types | N/A |
| Causes | Adenovirus |
| Risks | Immunocompromised, young children, crowded living conditions |
| Diagnosis | PCR, viral culture, serology |
| Differential diagnosis | Influenza, rhinovirus, respiratory syncytial virus |
| Prevention | Hand washing, vaccination (for military personnel) |
| Treatment | Supportive care, antiviral drugs (in severe cases) |
| Medication | N/A |
| Prognosis | Generally good, but can be severe in immunocompromised individuals |
| Frequency | Common |
| Deaths | N/A |
A viral infection caused by adenoviruses
Adenovirus infection is a type of viral infection caused by adenoviruses, which are a group of common viruses that infect the lining of the eyes, airways and lungs, intestines, urinary tract, and nervous system. Adenovirus infections can cause a wide range of illnesses, from mild respiratory infections to severe diseases.
Virology
Adenoviruses are medium-sized, non-enveloped viruses with an icosahedral nucleocapsid containing a double-stranded DNA genome. They are classified into seven species (A to G) and include more than 50 serotypes that can infect humans. Adenoviruses are known for their ability to cause infections in various tissues and organs.
Transmission
Adenoviruses are highly contagious and can spread through:
- Direct contact with an infected person
- Respiratory droplets from coughs or sneezes
- Contact with contaminated surfaces or objects
- Fecal-oral route, particularly in settings with poor sanitation
Clinical Manifestations
Adenovirus infections can present with a variety of symptoms depending on the site of infection:
Respiratory Infections
Adenoviruses are a common cause of respiratory illnesses, especially in children. Symptoms may include:
- Common cold symptoms
- Pharyngitis
- Bronchitis
- Pneumonia
Gastrointestinal Infections
Adenoviruses can cause gastroenteritis, particularly in young children, leading to:
- Diarrhea
- Vomiting
- Abdominal pain
Ocular Infections
Adenoviruses can cause eye infections such as:
- Conjunctivitis (pink eye)
- Keratoconjunctivitis
Other Infections
In rare cases, adenoviruses can cause:
Diagnosis
Diagnosis of adenovirus infection can be made through:
- PCR testing
- Viral culture
- Antigen detection tests
- Serology
Treatment
There is no specific antiviral treatment for adenovirus infections. Management is generally supportive and includes:
- Rest
- Hydration
- Over-the-counter medications to relieve symptoms
In severe cases, particularly in immunocompromised patients, antiviral medications such as cidofovir may be considered.
Prevention
Preventive measures include:
- Good hand hygiene
- Avoiding close contact with infected individuals
- Disinfection of contaminated surfaces
- Vaccination for military personnel against certain adenovirus serotypes
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Contributors: Prab R. Tumpati, MD
