Pediatric end-stage liver disease
Pediatric end-stage liver disease
Pediatric end-stage liver disease (PESLD), pronounced /pēˈdēˌatrik end-stāj ˈlivər diˈzēz/, is a severe, life-threatening condition in children that occurs when the liver is no longer able to perform its normal functions due to extensive damage. The term is often used to describe liver conditions that have progressed to a point where the organ is failing completely.
Etymology
The term "Pediatric end-stage liver disease" is derived from the Greek words pais (child), iatros (doctor), end (final), stage (step), liver (a large lobed glandular organ in the abdomen of vertebrates, involved in many metabolic processes), and disease (a disorder of structure or function in a human, animal, or plant, especially one that produces specific symptoms or that affects a specific location).
Related Terms
- Liver transplantation: A surgical procedure performed to replace a diseased liver with a healthy liver from another person.
- Hepatic encephalopathy: A decline in brain function that occurs as a result of severe liver disease.
- Portal hypertension: An increase in the blood pressure within a system of veins called the portal venous system.
- Cirrhosis: A late stage of scarring (fibrosis) of the liver caused by many forms of liver diseases and conditions.
- Hepatitis: Inflammation of the liver, commonly caused by a viral infection.
Symptoms
Symptoms of pediatric end-stage liver disease can vary widely, but may include jaundice, ascites (accumulation of fluid in the abdomen), varices (abnormally dilated vessels), and hepatic encephalopathy.
Diagnosis
Diagnosis of pediatric end-stage liver disease typically involves a combination of physical examination, medical history, and various diagnostic tests, including blood tests, imaging studies, and sometimes a liver biopsy.
Treatment
Treatment for pediatric end-stage liver disease often involves managing the symptoms and complications of the disease. In severe cases, a liver transplantation may be necessary.
External links
- Medical encyclopedia article on Pediatric end-stage liver disease
- Wikipedia's article - Pediatric end-stage liver disease
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