Opioid-induced hyperalgesia

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Opioid-induced hyperalgesia (pronunciation: oh-pee-oid in-duced hy-per-al-gee-za) is a medical condition characterized by an increased sensitivity to pain resulting from the prolonged use of opioids.

Etymology

The term "Opioid-induced hyperalgesia" is derived from three words. "Opioid", a class of drugs often used for their analgesic properties, "induced", meaning brought on by, and "hyperalgesia", a medical term for increased sensitivity to pain.

Definition

Opioid-induced hyperalgesia is a paradoxical response whereby a patient receiving opioids for the treatment of pain could actually become more sensitive to certain painful stimuli. This condition is characterized by a paradoxical response whereby a patient receiving analgesics for the treatment of pain paradoxically experiences an increased sensitivity to painful stimuli.

Symptoms

The symptoms of opioid-induced hyperalgesia can often mimic those of opioid withdrawal, including an increased sensitivity to pain, discomfort, and agitation.

Causes

The exact cause of opioid-induced hyperalgesia is not fully understood. However, it is believed to be related to the long-term use of opioids, which can alter the central nervous system's perception of pain.

Treatment

Treatment for opioid-induced hyperalgesia typically involves reducing or discontinuing the use of opioids. Other non-opioid medications and therapies may also be used to manage pain.

Related Terms

See Also

External links

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