Omeprazole/amoxicillin/rifabutin

Omeprazole/amoxicillin/rifabutin is a medication combination used in the treatment of Helicobacter pylori infection. This combination is marketed under the brand name Talicia.

Composition

The medication consists of three active ingredients:

• Omeprazole, a proton pump inhibitor (PPI) that reduces stomach acid production.
• Amoxicillin, an antibiotic that kills bacteria.
• Rifabutin, another antibiotic that kills bacteria.

Uses

Omeprazole/amoxicillin/rifabutin is used to treat Helicobacter pylori infection, a bacterial infection that can cause stomach ulcers and is associated with stomach cancer.

Mechanism of action

Omeprazole reduces the production of stomach acid, which makes the environment less hospitable for Helicobacter pylori. Amoxicillin and rifabutin kill the bacteria directly.

Side effects

Common side effects of omeprazole/amoxicillin/rifabutin include diarrhea, headache, nausea, abdominal pain, rash, and taste disturbance.

See also

• Helicobacter pylori
• Proton pump inhibitor
• Antibiotic

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