Nuclear pharmacy
A branch of pharmacy focused on the preparation and dispensing of radioactive materials for medical use
Nuclear pharmacy is a specialized area of pharmacy practice dedicated to the compounding and dispensing of radiopharmaceuticals. These are radioactive drugs used for diagnosis and therapy in the field of nuclear medicine. Nuclear pharmacists are responsible for ensuring the safe and effective use of these substances, which require unique handling and preparation techniques due to their radioactive nature.
History
The development of nuclear pharmacy began in the mid-20th century, paralleling advances in nuclear medicine. The first radiopharmaceuticals were used in the 1940s, and the field has grown significantly since then. The establishment of nuclear pharmacy as a recognized specialty occurred in the 1970s, with the creation of training programs and certification processes.
Radiopharmaceuticals
Radiopharmaceuticals are compounds that contain a radioactive isotope. They are used in both diagnostic and therapeutic procedures. In diagnostics, they help visualize and measure the function of organs and tissues, while in therapy, they deliver targeted radiation to treat conditions such as cancer.
Diagnostic Radiopharmaceuticals
Diagnostic radiopharmaceuticals are used in imaging techniques such as positron emission tomography (PET) and single-photon emission computed tomography (SPECT). These agents are designed to emit gamma rays or positrons, which can be detected by imaging equipment to provide detailed pictures of the body's internal structures.
Therapeutic Radiopharmaceuticals
Therapeutic radiopharmaceuticals deliver radiation directly to diseased cells, minimizing damage to surrounding healthy tissue. They are used in the treatment of various cancers, including thyroid cancer and non-Hodgkin's lymphoma.
Role of the Nuclear Pharmacist
Nuclear pharmacists are responsible for the preparation, quality control, and dispensing of radiopharmaceuticals. They must ensure that these substances are prepared in a sterile environment and meet strict regulatory standards. Additionally, nuclear pharmacists provide education and consultation to healthcare providers and patients regarding the safe use of radiopharmaceuticals.
Safety and Regulations
Due to the radioactive nature of the materials involved, nuclear pharmacy is subject to stringent safety and regulatory requirements. Nuclear pharmacists must adhere to guidelines set by organizations such as the Nuclear Regulatory Commission (NRC) and the Food and Drug Administration (FDA). These regulations cover the handling, storage, and disposal of radioactive materials to protect both healthcare workers and patients.
Education and Certification
To become a nuclear pharmacist, one must complete a Doctor of Pharmacy (Pharm.D.) degree followed by specialized training in nuclear pharmacy. Certification is available through the Board of Pharmacy Specialties (BPS), which requires passing an examination and maintaining continuing education in the field.
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Contributors: Prab R. Tumpati, MD