Norfenefrine
Norfenefrine
Norfenefrine (pronounced: nor-fen-ef-rin), also known as meta-octopamine or 3,4-dihydroxyphenethylamine, is a catecholamine that functions as a sympathomimetic drug. It is a naturally occurring neurotransmitter in some animals and is used medically to increase blood pressure and cardiac output.
Etymology
The term "Norfenefrine" is derived from the Greek words "nor" meaning "normal" and "fenefrine" which is a derivative of "epinephrine", a hormone and neurotransmitter.
Usage
Norfenefrine is used in the treatment of hypotension (low blood pressure) and cardiac arrest (sudden stop in heart function). It works by stimulating the adrenergic receptors in the heart, causing an increase in heart rate and blood pressure.
Related Terms
- Catecholamine: A group of neurotransmitters that includes dopamine, norepinephrine, and epinephrine.
- Sympathomimetic: A class of drugs that mimic the effects of the sympathetic nervous system.
- Neurotransmitter: Chemicals that transmit signals from a neuron to a target cell across a synapse.
- Hypotension: A condition characterized by abnormally low blood pressure.
- Cardiac arrest: A sudden loss of blood flow resulting from the failure of the heart to effectively pump.
- Adrenergic receptor: A class of G protein-coupled receptors that are targets of many catecholamines like norepinephrine and epinephrine.
External links
- Medical encyclopedia article on Norfenefrine
- Wikipedia's article - Norfenefrine
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