Norethisterone acetate oxime
Norethisterone acetate oxime is a synthetic progestin and a derivative of norethisterone acetate. It is used in hormonal contraception and hormone replacement therapy.
Chemical Structure and Properties
Norethisterone acetate oxime is a steroid with a chemical structure similar to that of norethisterone. It is characterized by the presence of an oxime group, which distinguishes it from other derivatives. The molecular formula is C22H29NO3.
Pharmacology
Norethisterone acetate oxime acts as a progestogen, mimicking the effects of the natural hormone progesterone. It binds to progesterone receptors in the body, influencing the menstrual cycle and ovulation. This makes it effective in contraception and in the management of menstrual disorders.
Medical Uses
Norethisterone acetate oxime is primarily used in oral contraceptives and in hormone replacement therapy for menopause. It helps in regulating the menstrual cycle, reducing symptoms of premenstrual syndrome (PMS), and managing endometriosis.
Side Effects
Common side effects of norethisterone acetate oxime include nausea, headache, breast tenderness, and mood changes. Long-term use may increase the risk of thromboembolism, breast cancer, and cardiovascular disease.
See Also
References
External Links
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Contributors: Prab R. Tumpati, MD
