Nodular melanoma

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
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Nodular melanoma
Synonyms	N/A
Pronounce	N/A
Specialty	N/A
Symptoms	New, unusual growth or change in an existing mole
Complications	Metastasis, Death
Onset	Typically in adulthood
Duration	Can be rapid
Types	N/A
Causes	Ultraviolet radiation, Genetic factors
Risks	Fair skin, Family history of melanoma, Excessive sun exposure
Diagnosis	Skin biopsy, Dermatoscopy
Differential diagnosis	Basal cell carcinoma, Squamous cell carcinoma, Seborrheic keratosis
Prevention	Sun protection, Regular skin checks
Treatment	Surgical excision, Immunotherapy, Targeted therapy
Medication	N/A
Prognosis	Variable, depends on stage at diagnosis
Frequency	Less common than other types of melanoma
Deaths	N/A

Nodular melanoma evolution

Nodular Melanoma is a type of melanoma that is typically characterized by its rapid growth and vertical invasion. It is the second most common subtype of melanoma, accounting for approximately 15-30% of all cases.

Introduction

Nodular melanoma often presents as a firm, round or oval-shaped, darkly pigmented or occasionally amelanotic (lacking pigment) nodule. Unlike other types of melanoma, nodular melanoma tends to grow more vertically than horizontally, which can lead to a quicker invasion of the dermis and subcutaneous tissue. This rapid growth and invasion can make nodular melanoma more dangerous than other types of melanoma.

Symptoms

The most common symptom of nodular melanoma is a rapidly growing, darkly pigmented nodule. Other symptoms can include changes in the size, shape, or color of an existing mole, or the development of a new mole. The nodule may also be itchy or bleed.

Diagnosis

The diagnosis of nodular melanoma is typically made through a biopsy of the suspicious lesion. The biopsy is then examined under a microscope by a pathologist to confirm the diagnosis. Other diagnostic tests, such as imaging studies or a sentinel lymph node biopsy, may also be performed to determine the extent of the disease.

Treatment

The primary treatment for nodular melanoma is surgical removal of the tumor and a margin of normal tissue surrounding it. In some cases, additional treatments such as chemotherapy, immunotherapy, or radiation therapy may be recommended.

Prognosis

The prognosis for nodular melanoma depends on a number of factors, including the thickness of the tumor, the presence of ulceration, and whether the cancer has spread to the lymph nodes or other parts of the body.

See also

• Melanoma
• Skin cancer
• Biopsy
• Pathology

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