Nmda receptor antagonist

NMDA Receptor Antagonist

NMDA receptor antagonist (pronunciation: en-em-dee-ey ree-sep-tor an-tag-o-nist) is a class of anesthetics that work by inhibiting the activity of the N-Methyl-D-aspartate receptor (NMDAR). They are used in the treatment of a variety of neurological and psychiatric conditions.

Etymology

The term "NMDA receptor antagonist" is derived from the name of the receptor that these drugs inhibit, the N-Methyl-D-aspartate receptor. The term "antagonist" refers to the drug's ability to inhibit the activity of the receptor.

Mechanism of Action

NMDA receptor antagonists work by binding to the NMDA receptor, a type of glutamate receptor, and blocking the action of glutamate, a neurotransmitter that normally activates the receptor. This inhibition of the NMDA receptor can have a variety of effects on the nervous system, depending on the specific drug and the dosage used.

Uses

NMDA receptor antagonists are used in the treatment of a variety of conditions, including Alzheimer's disease, Parkinson's disease, schizophrenia, and depression. They are also used as anesthetics and in the treatment of chronic pain.

Side Effects

Common side effects of NMDA receptor antagonists include dizziness, nausea, and hallucinations. In rare cases, these drugs can cause serious side effects such as severe psychiatric symptoms and neurological damage.

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Nmda receptor antagonist

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