Neutrophilic lobular panniculitis
Neutrophilic lobular panniculitis (pronunciation: new-tro-fill-ik lob-u-lar pan-nick-u-li-tis) is a rare type of panniculitis that primarily affects the subcutaneous fat tissue.
Etymology
The term "Neutrophilic lobular panniculitis" is derived from three words: "Neutrophilic" refers to neutrophils, a type of white blood cell; "lobular" refers to the lobules of the fat tissue; and "panniculitis" is an inflammation of the fat tissue.
Definition
Neutrophilic lobular panniculitis is a condition characterized by inflammation of the subcutaneous fat tissue, primarily involving the lobules, with a predominance of neutrophils. It is often associated with systemic diseases such as rheumatoid arthritis, lupus erythematosus, and pancreatitis.
Symptoms
The symptoms of Neutrophilic lobular panniculitis can vary but often include tender, red nodules or plaques on the skin, fever, malaise, and sometimes weight loss. The skin lesions typically occur on the legs, but can also be found on the arms, trunk, and face.
Diagnosis
Diagnosis of Neutrophilic lobular panniculitis is typically made through a combination of clinical examination, patient history, and a skin biopsy. The biopsy will show inflammation of the fat lobules with a predominance of neutrophils.
Treatment
Treatment of Neutrophilic lobular panniculitis often involves managing the underlying systemic disease. This can include medications to reduce inflammation and suppress the immune system. In some cases, surgical removal of the affected skin may be necessary.
Related Terms
External links
- Medical encyclopedia article on Neutrophilic lobular panniculitis
- Wikipedia's article - Neutrophilic lobular panniculitis
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