Neuraminidase inhibitors
Neuraminidase Inhibitors
Neuraminidase inhibitors (pronunciation: new-rah-min-i-dase in-hib-i-tors) are a class of antiviral drugs that target the neuraminidase enzyme, preventing its function and thus inhibiting the spread of influenza viruses in the host organism.
Etymology
The term "Neuraminidase inhibitors" is derived from the name of the enzyme they inhibit, "Neuraminidase", and the term "inhibitor", which refers to substances that reduce the activity of a particular enzyme.
Function
Neuraminidase inhibitors work by blocking the function of neuraminidase, an enzyme found on the surface of influenza viruses. This enzyme is responsible for cleaving sialic acid residues on the host cell surface, a process necessary for the release of new virus particles. By inhibiting this enzyme, these drugs prevent the release of new viruses, thereby limiting the spread of infection.
Types
There are two main types of neuraminidase inhibitors: oseltamivir (trade name Tamiflu) and zanamivir (trade name Relenza). Both drugs are used for the treatment and prevention of influenza A and B.
Related Terms
- Antiviral drugs: Medications used to treat viral infections.
- Influenza viruses: A group of viruses that cause influenza in birds and mammals.
- Oseltamivir: An antiviral medication used to treat and prevent influenza A and B.
- Zanamivir: An antiviral medication used to treat and prevent influenza A and B.
External links
- Medical encyclopedia article on Neuraminidase inhibitors
- Wikipedia's article - Neuraminidase inhibitors
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