Neuraminidase inhibitor
Neuraminidase inhibitor
Neuraminidase inhibitors (pronunciation: /nʊərˈæmɪnɪˌdeɪz ɪnˈhɪbɪtər/) are a type of antiviral drug used in the treatment and prevention of influenza infections. They work by blocking the function of the neuraminidase enzyme, thereby preventing the virus from spreading within the body.
Etymology
The term "neuraminidase inhibitor" is derived from the name of the enzyme it inhibits, neuraminidase, and the term "inhibitor", which refers to a substance that reduces or stops the activity of another substance. The term "neuraminidase" itself is derived from "neuraminic acid", a type of sialic acid, and "-ase", a suffix used in biochemistry to denote enzymes.
Types of Neuraminidase inhibitors
There are several types of neuraminidase inhibitors, including:
- Oseltamivir (trade name Tamiflu)
- Zanamivir (trade name Relenza)
- Peramivir (trade name Rapivab)
- Laninamivir (trade name Inavir)
These drugs are used to treat both Influenza A and Influenza B viruses.
Mechanism of action
Neuraminidase inhibitors work by binding to the neuraminidase enzyme on the surface of the influenza virus. This prevents the enzyme from cleaving sialic acid, a substance needed by the virus to spread to other cells in the body. By blocking this action, neuraminidase inhibitors help to contain the infection and reduce the severity of symptoms.
Side effects
Like all medications, neuraminidase inhibitors can cause side effects. These may include nausea, vomiting, diarrhea, and in rare cases, psychiatric symptoms such as confusion or abnormal behavior. It is important to consult a healthcare provider for advice on potential side effects and interactions with other medications.
See also
External links
- Medical encyclopedia article on Neuraminidase inhibitor
- Wikipedia's article - Neuraminidase inhibitor
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