Nanotoxicology

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Nanotoxicology is the study of the toxicity of nanomaterials. Because of nanotechnology's large surface area to volume ratio, it may have chemical, physical, and biological properties that differ from those of their larger counterparts.

Overview

Nanotoxicological studies are intended to determine whether and to what extent these properties may pose a threat to the environment and to human beings. Nanoparticles, for example, have been found to be toxic to humans and other organisms, and have been shown to be capable of entering cells and altering their function.

History

The term "nanotoxicology" was coined in 2004. The field has grown rapidly since then, with a significant increase in the number of published studies.

Research

Research in nanotoxicology is largely focused on the study of the interaction between nanoparticles and biological systems. This includes the study of the absorption, distribution, metabolism, and excretion (ADME) of nanoparticles, as well as their effects on the immune system and the potential for genotoxicity.

Risks

The risks associated with nanomaterials are not yet fully understood. However, some studies have suggested that they may have the potential to cause harm to human health and the environment. This is due to their small size, which allows them to penetrate cells and tissues, and their large surface area, which can lead to increased reactivity.

Regulation

Regulation of nanomaterials is currently a topic of much debate. Some argue that existing regulations are sufficient to manage the risks associated with nanomaterials, while others argue that new, specific regulations are needed.

See also

References


External links

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Nanotoxicology

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Contributors: Prab R. Tumpati, MD