NOD mice
NOD Mice
NOD mice (pronounced: /nɒd/ maɪs), also known as Non-Obese Diabetic mice, are a breed of laboratory mice that are commonly used in medical and biological research. The term "NOD" is an acronym derived from the phrase "Non-Obese Diabetic".
Etymology
The term "NOD" is an acronym that stands for "Non-Obese Diabetic". This name was given to this breed of mice due to their propensity to develop diabetes, despite not being obese. The term "mice" is the plural form of "mouse", which is derived from the Old English word "mūs".
Description
NOD mice are genetically predisposed to develop Type 1 diabetes. They are often used in research to study the development and progression of diabetes, as well as potential treatments and preventions for the disease. NOD mice are also used in research related to autoimmune diseases, as they have a tendency to develop other autoimmune conditions in addition to diabetes.
Related Terms
- Type 1 diabetes: A chronic condition in which the pancreas produces little or no insulin.
- Autoimmune diseases: A condition arising from an abnormal immune response to a normal body part.
- Laboratory mice: Mice that are bred and kept for scientific research.
- Genetic predisposition: An increased likelihood of developing a particular disease based on a person's genetic makeup.
External links
- Medical encyclopedia article on NOD mice
- Wikipedia's article - NOD mice
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