Microneurography

Microneurography is a technique used in neuroscience to record electrical signals from inside individual nerve fibers in the nervous system. It was first developed in the 1960s by Per Åke Thomas Thunberg and colleagues. This technique allows for the study of the electrophysiology of the peripheral nervous system.

History

Microneurography was first developed in the 1960s by Per Åke Thomas Thunberg and colleagues. The technique was initially used to study the electrophysiology of the peripheral nervous system.

Technique

Microneurography involves the insertion of a microelectrode into a nerve to record electrical activity from individual nerve fibers. The microelectrode is typically a tungsten needle with a tip diameter of less than 0.5 micrometers. The needle is inserted into the nerve under direct vision using a microscope. Once the needle is in place, electrical signals from the nerve fibers can be recorded.

Applications

Microneurography has been used in a variety of research and clinical applications. It has been used to study the function of the peripheral nervous system in health and disease, to investigate the mechanisms of pain and sensory perception, and to assess the effects of drugs on nerve function.

Limitations

While microneurography is a powerful technique, it has some limitations. It is an invasive procedure that requires a high level of skill to perform. It can also be time-consuming and requires specialized equipment.

See also

• Neuroscience
• Electrophysiology
• Nervous system
• Nerve fiber
• Per Åke Thomas Thunberg

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  Microneurography experimental setup schematic

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  Spinal nerve Sympathetic ganglion