Methidathion
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Methidathion is an organophosphate insecticide and acaricide used primarily to control a wide range of insects and mites in a variety of crops. Methidathion acts by inhibiting the enzyme acetylcholinesterase, leading to an accumulation of acetylcholine in the nervous system, which can cause paralysis and death in insects.
Uses
Methidathion is used to control pests on a variety of crops including citrus fruits, cotton, olives, and vegetables. It is effective against a range of insect pests such as aphids, mites, and whiteflies.
Mechanism of Action
As an organophosphate, methidathion functions by inhibiting acetylcholinesterase, an enzyme essential for nerve function in insects. This inhibition leads to the accumulation of acetylcholine, causing continuous nerve impulses that eventually paralyze and kill the pest.
Health and Safety
Exposure to methidathion can pose significant health risks to humans. Symptoms of poisoning may include headache, dizziness, nausea, and at high exposures, respiratory failure or death. Due to these risks, it is important to handle methidathion with extreme care, using proper protective equipment and following safety guidelines strictly.
Environmental Impact
Methidathion is toxic to aquatic life and non-target organisms including birds and bees. Its use can lead to environmental contamination if not managed properly, including water pollution and harm to beneficial insects.
Regulation
Due to its toxicity, the use of methidathion is regulated in many countries. Users must comply with safety guidelines to minimize environmental impact and protect public health.
See Also
Methidathion vector
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Contributors: Prab R. Tumpati, MD
