Mazzotti reaction
Mazzotti Reaction
Mazzotti reaction (pronunciation: ma-zo-ti re-ac-tion) is a medical term referring to a post-treatment reaction observed in patients undergoing therapy for Onchocerciasis, also known as river blindness. The reaction is named after Italian physician Luigi Mazzotti, who first described the phenomenon in the mid-20th century.
Etymology
The term "Mazzotti reaction" is derived from the name of Luigi Mazzotti, an Italian physician who first described the reaction in 1948. The word "reaction" is derived from the Latin "reactio", meaning "a response".
Definition
Mazzotti reaction is a severe and often shocking reaction that can occur within the first week of treatment for Onchocerciasis with the medication Ivermectin. The reaction is characterized by fever, skin rash, pain, and severe itching. It is caused by the death of the microfilariae, the larval form of the parasite Onchocerca volvulus, and the body's subsequent inflammatory response.
Related Terms
- Onchocerciasis: A parasitic disease also known as river blindness, caused by the nematode Onchocerca volvulus.
- Ivermectin: An anti-parasitic medication used to treat a variety of parasitic infections, including Onchocerciasis.
- Onchocerca volvulus: A species of parasitic worm that causes Onchocerciasis.
- Microfilariae: The larval form of certain parasitic worms, including Onchocerca volvulus.
See Also
- Loa loa: Another parasitic worm that can cause similar reactions during treatment.
- Parasitic Diseases: A category of diseases caused by parasites, including Onchocerciasis.
External links
- Medical encyclopedia article on Mazzotti reaction
- Wikipedia's article - Mazzotti reaction
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