Marginal zone
Marginal Zone
The Marginal Zone (pronunciation: mahr-ji-nuhl zohn) is a region in the lymph node and spleen that is rich in B cells. It is an important part of the immune system, playing a crucial role in the body's defense against pathogens.
Etymology
The term "marginal zone" is derived from the Latin words "margo" meaning edge or border, and "zona" meaning belt or girdle. It refers to the location of this region at the edge or periphery of the lymph node or spleen.
Function
The Marginal Zone is primarily involved in the immune response to blood-borne antigens. It contains a high concentration of macrophages and dendritic cells, which are responsible for capturing and presenting antigens to B cells. This initiates the production of antibodies, a key component of the body's immune response.
Related Terms
- B cells: A type of white blood cell that produces antibodies in response to antigens.
- Macrophages: A type of white blood cell that engulfs and digests cellular debris, foreign substances, microbes, and cancer cells.
- Dendritic cells: Immune cells that process antigen material and present it on the surface to other cells of the immune system.
- Antibodies: Proteins produced by B cells that neutralize or destroy foreign substances in the body.
- Antigens: Substances that can trigger an immune response when detected by the body.
External links
- Medical encyclopedia article on Marginal zone
- Wikipedia's article - Marginal zone
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