Mammary-type myofibroblastoma

Mammary-type Myofibroblastoma (pronunciation: mam-uh-ree type my-oh-fib-ro-blast-oh-ma) is a rare, benign tumor that originates from the myofibroblast cells. It is named so due to its histological resemblance to the myofibroblastoma of the breast, although it can occur in extramammary locations.

Etymology

The term "Mammary-type Myofibroblastoma" is derived from its similarity to the myofibroblastoma found in the mammary gland. The term "myofibroblastoma" is a combination of three words: "myo" (muscle), "fibro" (fibrous tissue), and "blastoma" (a tumor originating from immature cells).

Description

Mammary-type Myofibroblastoma is a soft tissue tumor that is typically well-circumscribed and unencapsulated. It is composed of spindle-shaped myofibroblasts and a variable amount of collagen. The tumor cells are usually arranged in short fascicles or storiform patterns. The tumor is often associated with a significant amount of adipose tissue.

Clinical Presentation

Patients with Mammary-type Myofibroblastoma usually present with a painless, slow-growing mass. The tumor can occur in both males and females, and it has been reported in a wide age range, from young adults to the elderly.

Diagnosis

The diagnosis of Mammary-type Myofibroblastoma is usually made based on the histological examination of the tumor. Immunohistochemistry can also be used to confirm the diagnosis. The tumor cells are typically positive for Desmin, SMA, and CD34.

Treatment and Prognosis

The treatment of choice for Mammary-type Myofibroblastoma is surgical excision. The prognosis is generally excellent, as the tumor is benign and recurrence is rare after complete excision.

Related Terms

• Myofibroblast
• Tumor
• Breast
• Desmin
• SMA
• CD34
• Immunohistochemistry
• Collagen

External links

• Medical encyclopedia article on Mammary-type myofibroblastoma
• Wikipedia's article - Mammary-type myofibroblastoma

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