MURCS association

MURCS Association

MURCS Association (pronounced: /mɜːrks/ association) is a rare congenital disorder that primarily affects the reproductive and urinary systems in females. The name "MURCS" is an acronym that stands for the primary features of the disorder: Müllerian duct anomalies, Urinary tract anomalies, Renal agenesis, Cervicothoracic somite dysplasia, and Single umbilical artery.

Etymology

The term "MURCS" was first coined in 1979 by Duncan, Khong, Fai, and Atkin. It is an acronym that stands for the primary features of the disorder: Müllerian duct anomalies, Urinary tract anomalies, Renal agenesis, Cervicothoracic somite dysplasia, and Single umbilical artery.

Müllerian Duct Anomalies

Müllerian duct anomalies (MDAs) are a group of disorders that occur when the Müllerian ducts fail to develop normally. The Müllerian ducts are structures in the embryo that develop into the female reproductive tract, including the uterus, fallopian tubes, cervix, and the upper part of the vagina.

Urinary Tract Anomalies

Urinary tract anomalies are abnormalities of the kidneys, ureters, bladder, or urethra. In MURCS association, these anomalies can include renal agenesis (absence of one or both kidneys), duplicated or ectopic ureters, and other abnormalities of the urinary tract.

Renal Agenesis

Renal agenesis is a condition in which a newborn is missing one or both kidneys at birth. This condition is a common feature of MURCS association.

Cervicothoracic Somite Dysplasia

Cervicothoracic somite dysplasia is a condition that affects the development of the bones and muscles of the neck and upper chest. This condition is less common in MURCS association but can occur.

Single Umbilical Artery

Single umbilical artery (SUA) is a condition in which there is only one artery in the umbilical cord instead of the usual two. SUA is the most common umbilical cord anomaly and is often associated with other congenital anomalies, including MURCS association.

See Also

• Congenital disorder
• Reproductive system disease
• Urinary system disease

External links

• Medical encyclopedia article on MURCS association
• Wikipedia's article - MURCS association

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