MEK inhibitor

MEK inhibitor is a type of drug that inhibits the mitogen-activated protein kinase kinase (MEK). It is used in the treatment of various types of cancer, including melanoma, lung cancer, colorectal cancer, and thyroid cancer.

Mechanism of action

MEK inhibitors work by blocking the action of a protein called MEK, which is part of a pathway that helps cells to divide and survive. By inhibiting MEK, these drugs can stop cancer cells from growing and dividing.

Types of MEK inhibitors

There are several types of MEK inhibitors, including:

• Selumetinib
• Trametinib
• Cobimetinib
• Binimetinib

Each of these drugs has been approved by the Food and Drug Administration (FDA) for use in certain types of cancer.

Side effects

Like all drugs, MEK inhibitors can cause side effects. These can vary from person to person, but may include:

• Nausea
• Vomiting
• Diarrhea
• Fatigue
• Skin rash

See also

• Cancer treatment
• Chemotherapy
• Targeted therapy