List of progestogens

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(Redirected from List of steroidal progestogens)

Progestogens are a type of steroid hormone that bind to and activate the progesterone receptor. They play a key role in the menstrual cycle and pregnancy. This article provides a list of progestogens, which are classified into generations based on their time of introduction and structural similarity.

First Generation Progestogens[edit]

The first generation progestogens include progesterone and its derivatives. They are structurally similar to the natural hormone progesterone.

  • Progesterone: It is a natural hormone involved in the menstrual cycle, pregnancy, and embryogenesis.
  • Medroxyprogesterone acetate: It is a derivative of progesterone and is used in hormonal contraception and hormone therapy.

Second Generation Progestogens[edit]

The second generation progestogens are derivatives of 19-nortestosterone. They have enhanced potency and reduced androgenic activity.

  • Norethisterone: It is a synthetic progestogen used in birth control pills, menopausal hormone therapy, and for the treatment of gynecological disorders.
  • Levonorgestrel: It is used in emergency contraception, intrauterine devices, contraceptive implants, and combined oral contraceptives.

Third Generation Progestogens[edit]

The third generation progestogens have improved pharmacokinetics and reduced side effects.

  • Desogestrel: It is used in contraceptive pills and has less androgenic effects.
  • Gestodene: It is used in contraceptive pills and has less androgenic and metabolic effects.

Fourth Generation Progestogens[edit]

The fourth generation progestogens have selective progesterone receptor modulator activity.

  • Drospirenone: It is used in contraceptive pills and has antiandrogenic and antimineralocorticoid effects.
  • Dienogest: It is used in contraceptive pills and for the treatment of endometriosis.

See Also[edit]

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