Linkage
Linkage (Medicine)
Linkage (pronunciation: /ˈlɪŋkɪdʒ/) is a term used in the field of Genetics and Medicine to describe the tendency of DNA sequences that are close together on a chromosome to be inherited together during the meiosis process. The term was first introduced by the British geneticist Thomas Hunt Morgan.
Etymology
The term "linkage" is derived from the English word "link", which means to connect or join. In the context of genetics, it refers to the connection or association between genes or DNA sequences on a chromosome.
Related Terms
- Genetic Linkage Map: A map of the relative positions of genetic loci on a chromosome, determined on the basis of how often the loci are inherited together.
- Linkage Disequilibrium: The non-random association of alleles at two or more loci, not necessarily on the same chromosome.
- Linkage Analysis: A method used in molecular biology to study the co-segregation of traits, including diseases, with genetic markers.
- Recombination: The process by which genetic material is physically mixed during sexual reproduction.
- Locus (genetics): A specific location of a gene or DNA sequence on a chromosome.
- Allele: One of two or more versions of a gene that are found at the same place on a chromosome.
See Also
External links
- Medical encyclopedia article on Linkage
- Wikipedia's article - Linkage
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