Latent autoimmune diabetes in adults

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Latent Autoimmune Diabetes in Adults (LADA)

Latent Autoimmune Diabetes in Adults (LADA), also known as Type 1.5 Diabetes, is a form of diabetes mellitus type 1 that occurs in adulthood, often with a slower course of onset. Pronounced as /ˈleɪtənt ˌɔːtɵˈiːmjuːn daɪəˈbiːtiːz ɪn ˈædʌlts/.

Etymology

The term "latent autoimmune diabetes in adults" is derived from the Latin word "latens" meaning "lying hidden", the Greek word "auto" meaning "self", and the Latin word "diabētēs" which was derived from the Ancient Greek "διαβαίνειν" (diabaínein), meaning "to pass through".

Definition

LADA is a slow-progressing form of autoimmune diabetes. Like the autoimmune disease type 1 diabetes, LADA occurs because your body's immune system attacks and destroys the insulin-producing beta cells in the pancreas. However, LADA also shares some characteristics with type 2 diabetes. For instance, LADA patients are often older than 30 and initially may be misdiagnosed as having type 2 diabetes based on their age, particularly if they have risk factors for type 2 diabetes such as a strong family history or obesity.

Symptoms

The symptoms of LADA are similar to those of both type 1 and type 2 diabetes, which include increased thirst, frequent urination, fatigue, blurred vision, and unexplained weight loss. However, the symptoms of LADA progress more slowly than those of type 1 diabetes and may require insulin treatment at diagnosis.

Diagnosis

Diagnosis of LADA is based on three criteria: age of onset, presence of Islet Cell Antibodies (ICA), and the need for insulin therapy within the first six months of diagnosis.

Treatment

Treatment for LADA typically includes a healthy diet, regular physical activity, and insulin therapy. Oral medications for type 2 diabetes may be used but are often not effective long-term.

Related Terms

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