Lamin A
Lamin A
Lamin A (pronounced: LAH-min A) is a type of protein that is found in the nuclear envelope of a cell. It is a crucial component of the nuclear lamina, a protein network that provides structural support to the nucleus.
Etymology
The term "Lamin A" is derived from the Latin word 'lamina', which means 'thin layer'. This is in reference to the protein's location in the thin layer of the nuclear envelope.
Function
Lamin A plays a vital role in the structural organization and function of the nucleus. It is involved in various nuclear activities including DNA replication, DNA repair, and gene expression. Lamin A also plays a role in the mechanical stability of the nucleus and helps to regulate the cell cycle.
Related Terms
- Laminopathy: A group of rare genetic disorders caused by mutations in the genes encoding lamins.
- Progeria: A rare, progressive genetic disorder that causes children to age rapidly, starting in their first two years of life. Mutations in the Lamin A gene are responsible for this condition.
- Hutchinson-Gilford Progeria Syndrome: A specific type of progeria caused by a mutation in the Lamin A gene.
- Nuclear Lamina: The network of lamin proteins, including Lamin A, that provides structural support to the nucleus.
See Also
External links
- Medical encyclopedia article on Lamin A
- Wikipedia's article - Lamin A
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