Knuckle pads

Knuckle pads
Synonyms	Heloderma, Garrod's pads
Pronounce	N/A
Specialty	Dermatology
Symptoms	Thickening of the skin over the knuckles
Complications	N/A
Onset	Adolescence or adulthood
Duration	Chronic
Types	N/A
Causes	Genetic predisposition, repetitive trauma
Risks	Family history, manual labor
Diagnosis	Clinical examination, biopsy
Differential diagnosis	Callus, Dupuytren's contracture, Pachydermodactyly
Prevention	N/A
Treatment	Avoidance of trauma, topical treatments, surgical removal
Medication	N/A
Prognosis	Benign, non-progressive
Frequency	Rare
Deaths	N/A

Knuckle pads are a type of dermatological condition characterized by the development of firm, skin-colored nodules over the proximal interphalangeal joints (the middle joints of the fingers). They are benign and typically asymptomatic, but can be associated with various other conditions.

Causes and associated conditions

Knuckle pads can be idiopathic, meaning they occur without a known cause. However, they can also be associated with a variety of conditions. These include Dupuytren's contracture, a condition that causes the fingers to bend towards the palm, and Garrod's pads, which are similar nodules that develop on the back of the hands and feet. Knuckle pads can also be seen in Peyronie's disease, a condition that causes the penis to bend when erect, and Ledderhose disease, which causes similar nodules to develop on the feet.

Diagnosis and treatment

Diagnosis of knuckle pads is typically made based on the characteristic appearance of the nodules. In some cases, a biopsy may be performed to confirm the diagnosis and rule out other conditions. Treatment is usually not necessary, as knuckle pads are benign and do not cause symptoms. However, if the nodules are bothersome or associated with an underlying condition, treatment may be directed towards that condition. This can include physical therapy, surgery, or medication.

See also

• Dermatology
• Dupuytren's contracture
• Garrod's pads
• Peyronie's disease
• Ledderhose disease

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