Itolizumab

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Itolizumab

Itolizumab (pronounced as i-to-li-zu-mab) is a monoclonal antibody specifically designed for the treatment of various autoimmune diseases and inflammatory conditions. It is a humanized antibody that targets the CD6 molecule, a protein present on the surface of T cells, which are a type of white blood cell.

Etymology

The name "Itolizumab" is derived from the combination of "ito", an abbreviation for "immunomodulatory", "li", short for "linker", and "zumab", a common suffix for humanized monoclonal antibodies.

Usage

Itolizumab is used in the treatment of psoriasis, a chronic skin condition, and has been approved for emergency use in the treatment of cytokine release syndrome (CRS) in patients with moderate to severe COVID-19 symptoms. It works by suppressing the immune response, thereby reducing inflammation and improving symptoms.

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