Intracytoplasmic sperm injection

Intracytoplasmic Sperm Injection (pronunciation: in-tra-sy-to-plas-mic sperm in-jec-tion) is a medical procedure commonly used in in vitro fertilization (IVF).

Etymology

The term is derived from the Greek words intra meaning "within", cyto meaning "cell", and plasmic referring to the cytoplasm of the cell. The term "sperm injection" refers to the process of introducing sperm into the egg.

Procedure

Intracytoplasmic Sperm Injection (ICSI) involves the injection of a single sperm directly into the cytoplasm of a mature oocyte (egg) using a microinjection pipette (glass needle). This procedure is performed under a microscope and requires precision and expertise.

Indications

ICSI is primarily used in cases of severe male infertility, including low sperm count, poor sperm motility, or abnormal sperm morphology. It may also be used when sperm are unable to penetrate the egg naturally, in cases of oligospermia or azoospermia, or when previous attempts at IVF have failed.

Risks and Complications

While ICSI has significantly improved the chances of pregnancy for many couples, it is not without risks. These may include damage to the egg during the injection process, and increased risk of genetic abnormalities in the offspring.

Related Terms

• In Vitro Fertilization (IVF)
• Oocyte (Egg)
• Infertility
• Oligospermia
• Azoospermia

External links

• Medical encyclopedia article on Intracytoplasmic sperm injection
• Wikipedia's article - Intracytoplasmic sperm injection

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