Insulin-like growth factor 1 receptor
Insulin-like growth factor 1 receptor (IGF1R) is a protein that in humans is encoded by the IGF1R gene.
Pronunciation
The pronunciation of Insulin-like growth factor 1 receptor is /ˈɪnsjʊlɪn laɪk ˈɡroʊθ ˈfæktər wʌn rɪˈsɛptər/.
Etymology
The term "Insulin-like growth factor 1 receptor" is derived from its function and structure. It is a receptor that binds insulin-like growth factor 1, a protein that has a similar structure to insulin.
Function
The IGF1R is a receptor that has tyrosine kinase activity. It is involved in the transduction of signals from the cell surface to the inside of the cell, which leads to cell growth and survival. The IGF1R is activated by the binding of its ligand, insulin-like growth factor 1 (IGF1), which is produced in response to growth hormone.
Related Terms
- Insulin-like growth factor 1 (IGF1): A protein that is similar in structure to insulin and binds to the IGF1R.
- Tyrosine kinase: An enzyme that is part of the IGF1R and is involved in signal transduction.
- Signal transduction: The process by which a signal is transmitted from the cell surface to the inside of the cell.
- Growth hormone: A hormone that stimulates the production of IGF1.
See Also
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