Immunoproteomics

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Immunoproteomics (pronounced: im·​mu·​no·​pro·​te·​o·​mics) is a sub-discipline of proteomics that involves the study of the proteome in relation to the immune system. The term is derived from the words "immuno-", referring to the immune system, and "-proteomics", referring to the large-scale study of proteins.

Definition

Immunoproteomics is the application of proteomics technologies to the study of the immune system. This includes the identification and quantification of proteins involved in immune responses, as well as the analysis of protein-protein interactions and post-translational modifications in the context of immunity.

Applications

Immunoproteomics has a wide range of applications in biomedical research, including the study of autoimmune diseases, infectious diseases, allergies, and cancer immunology. It is also used in the development of vaccines and therapeutics, as well as in the discovery of new biomarkers for disease diagnosis and prognosis.

Techniques

Common techniques used in immunoproteomics include two-dimensional gel electrophoresis (2-DE), mass spectrometry (MS), and protein microarrays. These techniques allow for the separation, identification, and quantification of proteins, as well as the analysis of protein-protein interactions and post-translational modifications.

Related Terms

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