Hydrocodone/homatropine

Hydrocodone/homatropine is a pharmaceutical drug combination used in medicine for the treatment of cough and pain. It is a combination of hydrocodone, an opioid pain reliever, and homatropine, an anticholinergic agent.

Composition

The medication is composed of two active ingredients: hydrocodone, a semi-synthetic opioid derived from codeine, and homatropine, an anticholinergic derived from atropine. The combination of these two substances helps to alleviate symptoms of cough and pain.

Pharmacology

Hydrocodone works by binding to and activating the mu-opioid receptor in the brain, which results in analgesia (pain relief), euphoria, and feelings of relaxation. Homatropine, on the other hand, works by blocking the action of acetylcholine on smooth muscles and other tissues, thus reducing the secretions of certain organs and glands in the body.

Indications

Hydrocodone/homatropine is indicated for the symptomatic relief of cough and upper respiratory symptoms associated with allergy or a cold. It is also used for the relief of moderate to severe pain.

Side Effects

Like all medications, hydrocodone/homatropine can cause side effects. Common side effects include dizziness, lightheadedness, nausea, vomiting, and constipation. Serious side effects may include slow/shallow breathing, seizure, and signs of a serious allergic reaction.

Contraindications

Hydrocodone/homatropine should not be used in patients with a known hypersensitivity to hydrocodone or homatropine. It is also contraindicated in patients with severe asthma or breathing problems, or a blockage in the stomach or intestines.

See Also

• List of opioids
• List of anticholinergics

References

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