Hydramacin-1
Hydramacin-1
Hydramacin-1 (pronounced: hy-dra-ma-cin-one) is a small antimicrobial peptide (AMP) that is found in the freshwater cnidarian Hydra magnipapillata.
Etymology
The term "Hydramacin-1" is derived from the name of the organism in which it was first discovered, Hydra magnipapillata, and the suffix "-1" indicates that it was the first of its kind to be identified.
Function
Hydramacin-1 is known for its potent antimicrobial activity. It plays a crucial role in the innate immune system of Hydra magnipapillata, helping the organism to fend off harmful microbes. The peptide achieves this by disrupting the cell membrane of the microbes, leading to their death.
Structure
Hydramacin-1 is a small peptide composed of 36 amino acids. It has a unique structure that includes a compact disulfide core and a large number of positively charged residues, which are believed to contribute to its antimicrobial activity.
Related Terms
- Antimicrobial peptide: A small protein that has the ability to kill or inhibit the growth of microbes.
- Cnidarian: A group of aquatic animals that includes jellyfish, sea anemones, and hydras.
- Hydra magnipapillata: A species of freshwater hydra known for its regenerative abilities.
- Immune system: The body's defense system against harmful microbes and other foreign substances.
- Cell membrane: The outer layer of a cell that separates it from its environment and controls the movement of substances in and out of the cell.
- Amino acids: The building blocks of proteins.
- Disulfide: A type of chemical bond that often plays a role in the structure and function of proteins.
External links
- Medical encyclopedia article on Hydramacin-1
- Wikipedia's article - Hydramacin-1
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