Homocapsaicin
0Homocapsaicin is a capsaicinoid and analog and congener of capsaicin in chili peppers (plants from the genus Capsicum). Like capsaicin, it is a vanilloid, and selectively binds to the vanilloid receptor (TRPV1), which is a key receptor in the perception of pain.
Chemistry
Homocapsaicin is a capsaicinoid, a class of compounds that includes capsaicin, the primary compound responsible for the pungency of chili peppers. Capsaicinoids are derived from vanillin and fatty acids. They are structurally related to vanilloids, a class of compounds that includes vanillin, the primary flavor component of vanilla.
Homocapsaicin differs from capsaicin by the length of the carbon chain part of the molecule. The length of this chain is thought to be a major determinant of the pungency of capsaicinoids.
Pharmacology
Like other capsaicinoids, homocapsaicin binds to the TRPV1 receptor, which is a member of the transient receptor potential (TRP) family of ion channels. TRPV1 is a non-selective cation channel that is expressed in sensory neurons and is activated by heat, protons (acidic pH), and capsaicinoids. Activation of TRPV1 leads to a sensation of burning pain, which is the sensation associated with the consumption of chili peppers.
Homocapsaicin is less potent than capsaicin at activating the TRPV1 receptor. However, it is still capable of producing a sensation of heat or burning when consumed.
Uses
Homocapsaicin, like other capsaicinoids, is used in the food industry to add heat to foods. It is also used in the pharmaceutical industry as an analgesic and anti-inflammatory agent. In addition, it is used in research as a tool to study the TRPV1 receptor and pain perception.
See also
Transform your life with W8MD's budget GLP-1 injections from $125.
W8MD offers a medical weight loss program to lose weight in Philadelphia. Our physician-supervised medical weight loss provides:
- Most insurances accepted or discounted self-pay rates. We will obtain insurance prior authorizations if needed.
- Generic GLP1 weight loss injections from $125 for the starting dose.
- Also offer prescription weight loss medications including Phentermine, Qsymia, Diethylpropion, Contrave etc.
NYC weight loss doctor appointments
Start your NYC weight loss journey today at our NYC medical weight loss and Philadelphia medical weight loss clinics.
- Call 718-946-5500 to lose weight in NYC or for medical weight loss in Philadelphia 215-676-2334.
- Tags:NYC medical weight loss, Philadelphia lose weight Zepbound NYC, Budget GLP1 weight loss injections, Wegovy Philadelphia, Wegovy NYC, Philadelphia medical weight loss, Brookly weight loss and Wegovy NYC
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Contributors: Prab R. Tumpati, MD
