Hirano body
Hirano Body
Hirano body (pronunciation: hee-rah-noh body) is a type of intracellular inclusion found in the neurons of the brain. These bodies are named after the Japanese-American neuropathologist, Dr. Akiyoshi Hirano, who first described them in 1965.
Etymology
The term "Hirano body" is derived from the name of Dr. Akiyoshi Hirano, who first identified these structures during his research on Alzheimer's disease and other neurodegenerative diseases.
Description
Hirano bodies are eosinophilic (acid-staining), rod-shaped structures found in the dendrites of neurons. They are composed of actin, an actin-binding protein, and other proteins. The exact function of Hirano bodies is not fully understood, but they are often associated with aging and neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease.
Related Terms
- Neuron: A specialized cell transmitting nerve impulses; a nerve cell.
- Dendrite: A short branched extension of a nerve cell, along which impulses received from other cells at synapses are transmitted to the cell body.
- Intracellular: Located or occurring within a cell or cells.
- Neurodegenerative diseases: Diseases characterized by the progressive loss of structure or function of neurons, including death of neurons.
- Alzheimer's disease: A progressive disease that destroys memory and other important mental functions.
- Parkinson's disease: A progressive nervous system disorder that affects movement.
External links
- Medical encyclopedia article on Hirano body
- Wikipedia's article - Hirano body
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