Hemopoietic growth factor

Hemopoietic Growth Factor

The Hemopoietic Growth Factor (HGF) is a type of protein that stimulates the growth and differentiation of blood cells. These proteins are secreted by the bone marrow stromal cells and are essential for the production and function of white blood cells, red blood cells, and platelets.

Function

Hemopoietic Growth Factors are responsible for the regulation of hematopoiesis, the process by which the body produces blood cells. They stimulate the proliferation, differentiation, and survival of hematopoietic cells. The different types of HGFs include Erythropoietin (EPO), Granulocyte Colony-Stimulating Factor (G-CSF), Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF), Interleukin (IL), and Thrombopoietin (TPO).

Clinical Significance

Hemopoietic Growth Factors are used in the treatment of various blood disorders and cancers. They can help to increase the number of blood cells in patients undergoing chemotherapy or radiation therapy, and can also be used to stimulate the production of stem cells for stem cell transplantation.

See Also

• Erythropoietin
• Granulocyte Colony-Stimulating Factor
• Granulocyte-Macrophage Colony-Stimulating Factor
• Interleukin
• Thrombopoietin
• Hematopoiesis
• Stem cell transplantation

References

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