Hemihypertrophy
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
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| Hemihypertrophy | |
|---|---|
| Synonyms | Hemihyperplasia |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Asymmetrical growth of one or more parts of the body |
| Complications | Increased risk of Wilms' tumor, hepatoblastoma |
| Onset | Congenital |
| Duration | Lifelong |
| Types | N/A |
| Causes | Genetic mutation |
| Risks | Beckwith-Wiedemann syndrome, Proteus syndrome |
| Diagnosis | Physical examination, imaging studies, genetic testing |
| Differential diagnosis | Beckwith-Wiedemann syndrome, Klippel-Trenaunay syndrome |
| Prevention | N/A |
| Treatment | Orthopedic surgery, physical therapy |
| Medication | N/A |
| Prognosis | N/A |
| Frequency | Rare |
| Deaths | N/A |
Hemihypertrophy or hemihyperplasia is a condition where one side of the body grows more than the other due to an excess proliferation of cells, leading to asymmetry. This condition can affect several parts of the body, including the face, torso, limbs, and internal organs.
Causes
The exact cause of hemihypertrophy is unknown. However, it is believed to be a result of an abnormality in cell growth and division. Some cases have been associated with certain genetic conditions, such as Beckwith-Wiedemann syndrome and Proteus syndrome, but the majority of cases occur sporadically.
Symptoms
The primary symptom of hemihypertrophy is an observable difference in size between the two sides of the body. This can be present at birth or develop gradually over time. Other symptoms can vary widely depending on which parts of the body are affected. For example, if the condition affects the internal organs, it can lead to complications such as kidney disease or liver disease.
Diagnosis
Diagnosis of hemihypertrophy typically involves a physical examination and a review of the patient's medical history. Imaging tests, such as X-rays, CT scans, or MRI scans, may be used to confirm the diagnosis and assess the extent of the condition.
Treatment
Treatment for hemihypertrophy is usually aimed at managing the symptoms and preventing complications. This may involve regular monitoring, physical therapy, and in some cases, surgery to correct the size difference. In cases where the condition is associated with a genetic disorder, additional treatments may be necessary.
Prognosis
The prognosis for individuals with hemihypertrophy largely depends on the severity of the condition and the presence of any associated complications. With appropriate management, many individuals with this condition can lead normal, healthy lives.
See also
References
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Contributors: Prab R. Tumpati, MD