Gnathostoma hispidum
Gnathostoma hispidum is a species of parasitic worm belonging to the Gnathostoma genus. It is known to infect various mammalian hosts, including humans, and is primarily found in Asia and Latin America.
Life Cycle
The life cycle of Gnathostoma hispidum involves several stages and multiple hosts. The adult worms reside in the stomach of the definitive host, where they lay eggs. These eggs are then excreted in the feces of the host. Once in the environment, the eggs hatch into first-stage larvae, which are ingested by small crustaceans, the first intermediate hosts. Within these hosts, the larvae develop into the second stage. These infected crustaceans are then eaten by a second intermediate host, typically a fish or amphibian, where the larvae further develop. The cycle is completed when a definitive host, such as a human, consumes the infected second intermediate host.
Clinical Manifestations
In humans, infection with Gnathostoma hispidum can lead to a condition known as gnathostomiasis. This disease is characterized by migratory swelling and pain, and can also cause serious complications such as neurological disorders and eye diseases if the larvae migrate to the central nervous system or the eyes.
Diagnosis and Treatment
Diagnosis of Gnathostoma hispidum infection is typically made through the identification of larvae in tissue samples, or through serological testing. Treatment usually involves the administration of anthelmintic drugs, such as ivermectin or albendazole.
Prevention
Prevention of Gnathostoma hispidum infection primarily involves avoiding the consumption of raw or undercooked fish or amphibians in areas where the parasite is endemic.
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Contributors: Prab R. Tumpati, MD