Genomic instability
| Genomic instability | |
|---|---|
| Term | Genomic instability |
| Short definition | genomic characterization (jeh-NOH-mik KAYR-ik-ter-rih-ZAY-shun) A laboratory method that uses a sample of tissue, blood, or other body fluid to learn more about to learn all the genes in a person or a specific cell type and how those genes interact with each other and with the environment. Genomic characterization can be done to find out why some people get certain diseases and others don't. |
| Type | Cancer terms |
| Specialty | Oncology |
| Language | English |
| Source | NCI |
| Comments | |
genomic instability - (pronounced) (jeh-NOH-mik in-stuh-BIH-lih-tee) The increased tendency for DNA mutations (changes) and other genetic changes to occur during cell division. Genomic instability is caused by defects in certain processes that control cell division. It occurs in many types of cancer. These defects can include mutations in certain genes involved in repairing damaged DNA, or errors that are not corrected when DNA is copied into a cell. They can also contain defects such as broken, missing, rearranged, or extra chromosomes. Studying genomic instability can help researchers understand how certain diseases, such as cancer, develop. This can lead to new ways of diagnosing, treating and preventing disease
External links
- Medical encyclopedia article on Genomic instability
- Wikipedia's article - Genomic instability
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