Frederick Kaplan

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Frederick Kaplan

Dr. Frederick S. Kaplan

Frederick S. Kaplan is a renowned American physician and researcher, best known for his groundbreaking work in the field of genetic disorders, particularly fibrodysplasia ossificans progressiva (FOP). He holds the position of the Isaac & Rose Nassau Professor of Orthopaedic Molecular Medicine at the Perelman School of Medicine at the University of Pennsylvania.

Early Life and Education

Frederick Kaplan was born in the United States and developed an early interest in medicine and science. He pursued his undergraduate studies at Johns Hopkins University, where he graduated with a degree in biology. He then attended the Johns Hopkins School of Medicine, earning his MD degree.

Career

After completing his medical degree, Kaplan undertook residency training in orthopaedic surgery at the Hospital of the University of Pennsylvania. He further specialized in molecular genetics and orthopaedic research, which laid the foundation for his future work in rare genetic diseases.

Research on Fibrodysplasia Ossificans Progressiva

Kaplan's most notable contribution to medical science is his research on fibrodysplasia ossificans progressiva (FOP), a rare and debilitating genetic disorder characterized by the abnormal development of bone in muscles, tendons, and other connective tissues. His work led to the identification of the ACVR1 gene mutation responsible for FOP, a discovery that has opened new avenues for understanding and potentially treating this condition.

Academic Contributions

In addition to his research, Kaplan has been a dedicated educator, mentoring numerous students and fellows in the field of orthopaedic molecular medicine. He has published extensively in scientific journals and has been a keynote speaker at various international conferences on genetic disorders and orthopaedic research.

Awards and Honors

Kaplan's contributions to medicine and science have been recognized with numerous awards and honors. He has received accolades from prestigious organizations such as the American Academy of Orthopaedic Surgeons and the National Institutes of Health.

Personal Life

Frederick Kaplan is married and has children. He is known for his passion for teaching and his commitment to advancing medical research. Outside of his professional life, he enjoys reading and spending time with his family.

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Contributors: Prab R. Tumpati, MD