Fluorophore

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Fluorophore

Fluorophore (/flʊəˈrɒfɔːr/), also known as a fluorescent dye or fluorescent probe, is a chemical compound that can re-emit light upon light excitation.

Etymology

The term "Fluorophore" comes from the Latin fluere, meaning "to flow", and the Greek phoros, meaning "bearer".

Definition

Fluorophores are typically composed of several combined aromatic groups, and their ability to re-emit light is a result of their molecular structure. They are extensively used in various scientific research and diagnostic methods, such as fluorescence microscopy, flow cytometry, fluorescence correlation spectroscopy, and fluorescence in situ hybridization (FISH).

Types of Fluorophores

There are several types of fluorophores, including organic compounds, proteins, and quantum dots. Some fluorophores are naturally occurring, such as green fluorescent protein (GFP), while others are synthetically produced, like rhodamine and fluorescein.

Related Terms

  • Fluorescence: The emission of light by a substance that has absorbed light or other electromagnetic radiation.
  • Chromophore: The part of a molecule responsible for its color.
  • Spectroscopy: The study of the interaction between matter and electromagnetic radiation.

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