Filaggrin
Filaggrin (pronounced: /fɪˈlæɡrɪn/) is a filament-associated protein that binds to keratin fibers in epithelial cells. It plays a crucial role in the skin's barrier function.
Etymology
The term "Filaggrin" is derived from the words "filament" and "aggregating", reflecting its function in the skin's structure.
Function
Filaggrin is essential for the proper formation of the stratum corneum, the outermost layer of the epidermis. It aids in the aggregation of keratin filaments, which are necessary for the structural integrity of the skin, nails, and hair.
Related Terms
- Epidermis: The outermost layer of the skin, where filaggrin is found.
- Keratin: A type of protein that filaggrin binds to in the skin.
- Stratum corneum: The outermost layer of the epidermis, which filaggrin helps to form.
Health Implications
Mutations in the FLG gene, which codes for filaggrin, have been associated with skin conditions such as ichthyosis vulgaris and atopic dermatitis. Reduced levels of filaggrin have also been observed in the skin of individuals with psoriasis.
See Also
External links
- Medical encyclopedia article on Filaggrin
- Wikipedia's article - Filaggrin
This WikiMD dictionary article is a stub. You can help make it a full article.
Languages: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
Urdu,
বাংলা,
తెలుగు,
தமிழ்,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
European
español,
Deutsch,
français,
русский,
português do Brasil,
Italian,
polski