Fibrin ring granuloma

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Fibrin Ring Granuloma

Fibrin Ring Granuloma (pronunciation: /ˈfaɪ.brɪn rɪŋ ˌgræn.jʊˈloʊ.mə/) is a unique pathological entity characterized by the presence of a necrotic center surrounded by a ring of fibrin and histiocytes.

Etymology

The term "Fibrin Ring Granuloma" is derived from the Latin words 'fibra' meaning fiber, 'ring' meaning circle, and 'granuloma' meaning small nodular inflammation in the tissue.

Definition

Fibrin Ring Granuloma is a specific type of granuloma that is characterized by a central area of necrosis surrounded by a ring of fibrin. This is often associated with certain infections and conditions such as Q fever, visceral leishmaniasis, and Hodgkin's disease.

Clinical Significance

Fibrin Ring Granulomas are often found in patients with Q fever, an infection caused by the bacterium Coxiella burnetii. They can also be seen in visceral leishmaniasis, a disease caused by protozoan parasites of the genus Leishmania, and in Hodgkin's disease, a type of lymphoma.

Related Terms

  • Granuloma: A granuloma is a small area of inflammation due to tissue injury.
  • Fibrin: Fibrin is a protein involved in the clotting of blood.
  • Q fever: Q fever is a disease caused by infection with Coxiella burnetii, a bacterium that affects humans and other animals.
  • Visceral leishmaniasis: Visceral leishmaniasis is a disease caused by protozoan parasites of the genus Leishmania.
  • Hodgkin's disease: Hodgkin's disease is a type of lymphoma, which is a cancer of the lymphatic system.

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