Factor v leiden

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Factor V Leiden

Factor V Leiden (pronounced: Factor Five Leiden) is a mutation of one of the clotting factors in the blood called factor V. This particular mutation can increase your chance of developing abnormal blood clots (thrombophilia), which can lead to conditions such as deep vein thrombosis or pulmonary embolism.

Etymology

The term "Factor V Leiden" is named after the city of Leiden, where the university is located that made the discovery in 1994. The "V" stands for five, as factor V is one of the numerous coagulation factors needed for blood to clot.

Related Terms

  • Thrombophilia: An abnormality of blood coagulation that increases the risk of thrombosis (blood clots in blood vessels).
  • Deep vein thrombosis (DVT): A blood clot that forms in a vein deep in the body, most often in the leg.
  • Pulmonary embolism (PE): A blockage in one of the pulmonary arteries in the lungs, usually due to a blood clot that traveled from a leg.
  • Coagulation: The process by which blood changes from a liquid to a gel, forming a clot.
  • Mutation: A change in a DNA sequence, usually occurring because of errors in replication or repair.

See Also

External links

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