Factor Va
Factor Va
Factor Va (pronounced as "factor five a") is a coagulation factor that plays a crucial role in the blood clotting process. It is an activated form of Factor V, a larger protein that is cleaved to produce Factor Va and Factor Vb.
Etymology
The term "Factor Va" originates from the Latin word "factor", meaning "maker" or "doer", and the Roman numeral "V", which stands for 5, followed by the lowercase "a". This nomenclature is used to denote the activated form of Factor V.
Function
Factor Va serves as a cofactor for Factor Xa in the conversion of prothrombin to thrombin, a key enzyme in the coagulation cascade. This process is essential for the formation of a stable blood clot following vascular injury.
Related Terms
- Factor V Leiden: A mutation of Factor V that leads to a hypercoagulable state.
- Prothrombin Time (PT): A test that measures how long it takes for clot formation, which can be affected by the levels of Factor Va.
- Activated Partial Thromboplastin Time (aPTT): Another test that measures clotting time and can be influenced by Factor Va levels.
See Also
External links
- Medical encyclopedia article on Factor Va
- Wikipedia's article - Factor Va
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