Extranuclear inheritance
Extranuclear inheritance is a form of genetic inheritance that occurs outside the nucleus of a cell. This type of inheritance is non-Mendelian and involves genes located in organelles such as mitochondria and chloroplasts.
Overview
Extranuclear inheritance, also known as cytoplasmic inheritance, is a form of transmission of genetic traits that does not involve the nucleus. This is in contrast to the traditional Mendelian inheritance which involves genes located in the nucleus of the cell.
In extranuclear inheritance, the genetic information is transmitted through the cytoplasm of the cell, specifically through organelles such as mitochondria and chloroplasts. These organelles have their own DNA, separate from the nuclear DNA, and can therefore transmit genetic traits independently.
Mitochondrial Inheritance
Mitochondrial inheritance is a form of extranuclear inheritance where the genetic traits are passed on through the mitochondria. Mitochondria are unique in that they have their own DNA, separate from the nuclear DNA. This mitochondrial DNA is inherited exclusively from the mother, as the mitochondria in the sperm are typically destroyed after fertilization.
Chloroplast Inheritance
Chloroplast inheritance is another form of extranuclear inheritance, specifically in plants. Like mitochondria, chloroplasts also have their own DNA. However, the pattern of inheritance can vary depending on the species. In some species, chloroplasts are inherited from the mother, while in others they are inherited from the father or both parents.
Implications
Extranuclear inheritance has important implications in the study of genetics. It provides a different perspective on inheritance patterns and can help explain certain genetic phenomena that cannot be explained by Mendelian inheritance alone. For example, certain genetic diseases are caused by mutations in mitochondrial DNA and are therefore inherited in a non-Mendelian manner.
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Contributors: Prab R. Tumpati, MD