Ewing

From WikiMD's medical encyclopedia

A type of cancerous tumor


Ewing sarcoma
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Synonyms
Pronounce N/A
Field Oncology
Symptoms Pain, swelling, fever
Complications Metastasis
Onset
Duration
Types
Causes Genetic mutation
Risks
Diagnosis Biopsy, imaging studies
Differential diagnosis
Prevention
Treatment Chemotherapy, radiation therapy, surgery
Medication
Prognosis
Frequency
Deaths


Ewing sarcoma is a rare type of cancer that occurs in bones or in the soft tissue around the bones. It primarily affects children and young adults. The tumor is named after James Ewing, the American pathologist who first described it in 1921.

Symptoms

The most common symptoms of Ewing sarcoma include:

Causes

Ewing sarcoma is caused by a genetic mutation that occurs after birth. This mutation involves a translocation between chromosomes 11 and 22, which leads to the formation of an abnormal fusion gene.

Diagnosis

Diagnosis of Ewing sarcoma typically involves:

  • Biopsy: A sample of the tumor is taken and examined under a microscope.
  • Imaging studies: Techniques such as X-ray, MRI, and CT scan are used to determine the size and location of the tumor.

Treatment

Treatment for Ewing sarcoma usually involves a combination of:

  • Chemotherapy: The use of drugs to kill cancer cells.
  • Radiation therapy: The use of high-energy rays to destroy cancer cells.
  • Surgery: The removal of the tumor and some surrounding healthy tissue.

Prognosis

The prognosis for Ewing sarcoma depends on several factors, including the size and location of the tumor, whether the cancer has spread, and the patient's overall health. Early diagnosis and treatment improve the chances of a favorable outcome.

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Contributors: Prab R. Tumpati, MD