Estradiol hemisuccinate/progesterone
Estradiol hemisuccinate/progesterone is a combination of estradiol hemisuccinate and progesterone, two hormones used in hormone therapy.
Etymology
The term "estradiol" is derived from estra-, a reference to estrus, and -diol, a chemical term and suffix indicating that the compound contains two alcohol groups. The term "progesterone" is derived from progestational steroidal ketone, indicating its role in gestation and its chemical structure.
Estradiol hemisuccinate
Estradiol hemisuccinate is a form of estradiol, the primary female sex hormone. It is a hemisuccinate ester of estradiol, which means it is a compound formed from estradiol and succinic acid. Estradiol hemisuccinate is often used in hormone therapy for menopausal symptoms and in transgender hormone therapy.
Progesterone
Progesterone is a hormone involved in the menstrual cycle, pregnancy, and embryogenesis. It is often used in combination with estradiol in hormone therapy.
Combination therapy
The combination of estradiol hemisuccinate and progesterone is used in hormone therapy, particularly for the treatment of menopausal symptoms. The estradiol component helps to alleviate symptoms such as hot flashes and night sweats, while the progesterone component helps to protect the uterus from the effects of estradiol.
Related terms
- Estradiol: The primary female sex hormone.
- Progesterone: A hormone involved in the menstrual cycle, pregnancy, and embryogenesis.
- Hormone therapy: The use of hormones in medical treatment.
- Menopause: The time in most women's lives when menstrual periods stop permanently, and they are no longer able to bear children.
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Contributors: Prab R. Tumpati, MD